In order to control the global cancer burden, it is important to address the burden of cancer in low- and middle-income countries (LMICs). But global oncology is not the concern of LMICs alone. A recent article by Kostelecky et al in Journal of Global Oncology highlights an important pillar of global oncology—partnerships between high-income countries (HICs) and LMICs to improve cancer care and research in LMICs. Read the accompanying editorial by Bishal Gyawali and Gilberto Lopes for important takeaways from the article for future HIC-LMIC collaborations.