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Genetic Analysis of the Multidrug Resistance Phenotype in Tumor Cells

Michael Gottesman

2 Collaborator(s)

Funding source

National Cancer Institute (NIH)
To study the function of new agents that kill MDR1-expressing cells

Related projects

Andrew Gregory Sikora

TARGETING INOS TO INHIBIT MYELOID-DERIVED SUPPRESSOR CELLS (MDSC) IN MELANOMA

Melanoma of skin

Hongbo Chi

Tsc1/mTOR axis in immune homeostasis and tumorigenesis

Leukaemia

William Stetler-Stevenson

Preclinical development of TIMP-2 as a biologic therapy for cancer

Brain, nervous system

Peter Demant

Genetic components of adverse effects of cisplatin therapy

Melanoma of skin

Raymond J Deshaies

Role of CSN in the activity and dynamic cycling of cullin-RING ubiquitin ligases

Melanoma of skin

Rameen Beroukhim

Genetic evolution of glioblastomas during radiation and temozolomide therapy

Brain, nervous system

Christophe P Nicot

HTLV-I Tax induces DNA Breaks and Inhibits HR Repair through Activation of NF-kB

Leukaemia

Hematology and hematologic malignancies Pathology

Mitchell Ho

Development of antibody-based cancer therapies

Liver and intrahepatic bile ducts

Pathology

Xuefang Cao

Targeting Granzyme B to Separate GVH from GVL Responses

Leukaemia