The purpose of this shared resource is to collect and distribute clinically annotated human biospecimens related to cervical cancer and HPV disease, and to provide expertise and support for investigators in the Johns Hopkins/University of Alabama/University of Colorado Cervical Cancer SPORE to perform specialized histopathologic, immunohistochemical, and molecular analyses. This core will Centrealize the specimen acquisition and processing resources as well as tissue-based analyses for the five projects of the Cervical Cancer SPORE.