Ontario Institute for Cancer Research
OICR

Laurie Ailles

Tumour-Initiating Cells in Oral Cancer Patients: Predictors of Outcome and Identification of Candidate Therapeutic Targets

Lip, oral cavity

Senthil Muthuswamy

To investigate the role played by JAM-A in ErbB2-mediated tumorigenesis

Melanoma of skin All cancers but non-melanoma skin cancer

Faiyaz Notta

The role of tumour-associated stroma in human pancreatic cancer pathogenesis

Pancreas

Benjamin Neel

The Gab/Par pathway in development and cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Robert Rottapel

The Architecture of Feedback Signaling Networks in Normal and Cancer Cells

Melanoma of skin All cancers but non-melanoma skin cancer

Catherine O'Brien

Targeting colorectal cancer-initiating cells and anti-EGFR therapeutic resistance by manipulating levels of the reactive aldehyde, 4-hydroxynonenal.

Colorectum

Paul Boutros

Systems Biology of Tumour Hypoxia

Melanoma of skin All cancers but non-melanoma skin cancer

Che-Wei Chang

Systematic identification of resistance mechanisms to HER2-targeted therapies in breast cancer.

Breast

Gilbert Prive

Structural and functional studies of membrane transporters

Melanoma of skin All cancers but non-melanoma skin cancer

Benjamin Neel

Role of PTP1B in Her2+ breast cancer

Breast

Pathology

Gang Zheng

Porphysome nanoparticle-enabled minimally invasive transbronchial photothermal ablation of lung cancer

Trachea, bronchus and lung

I. Alex Vitkin

Optical coherence tomography for assessment of early radiobiological response in-vivo

Melanoma of skin All cancers but non-melanoma skin cancer

Radiation Oncology

Michael Herman Chui

Novel therapeutic targets for CCNE1-amplified high-grade serous ovarian carcinomas

Ovary

Dharmendra Dingar

In vivo BioID identifies novel c-MYC interacting partners

Trachea, bronchus and lung Leukaemia Colorectum Breast

Gang Zheng

Improving cure rate of early stage lung cancer with personalized nanomedicine

Trachea, bronchus and lung

Thomas Hudson

High resolution genetic analysis of genetic loci implicated in colorectal cancer

Colorectum

Michelle Brazas

Gaining informatics skills to support translational cancer research: Canadian Bioinformatics Workshop on Cancer Genomics 2014

Melanoma of skin All cancers but non-melanoma skin cancer

Robert Rottapel

Elucidation of the role of the RhoGEF Lfc in human epithelial tumors

Ovary

Lincoln Stein

Early detection of patients at high risk of esophageal adenocarcinoma

Oesophagus

Paul Krzyzanowski

Development of a genomic signature to identify progression of Barrett's Esophagus to Esophageal Adenocarcinoma

Oesophagus

Ankit Sinha

A novel N-glyco-proteomics driven strategy to identify tumour secreted proteins using patient-derived xenografts.

Ovary

David H Haussler

Center for Big Data in Translational Genomics

Leukaemia Breast

Meenhard F Herlyn

Human Melanoma: Etiology, Progression and Therapy

Melanoma of skin

Pathology

Tony E Godfrey

Feasibility of Molecular Cytology for the Management of Barrett's Esophagus

Oesophagus

Radiation Oncology

Shyh-Dar Li

Stromal Depletion for Pancreatic Cancer Therapy

Pancreas

Pathology

Alana L Welm

Short-form Ron Kinase in Tumor Progression and Metastasis

Breast

Ulrike Peters

Molecular Pathological Epidemiology of Colorectal Cancer

Colorectum

Irene Andrulis

LEGACY: A Cohort of Youth in Families from the Breast Cancer Family Registry

Breast

Radiation Oncology Pediatric oncology or childhood cancer

James C Paulson

In vivo Targeting of Hematopoetic Cells With Glycan Ligands of Siglecs

Non-Hodgkin lymphoma Leukaemia

Hematology and hematologic malignancies

Meenhard F Herlyn

Human Melanoma: Etiology, Progression and Therapy

Melanoma of skin

Pathology

Weiva Sieh

Genome-Wide Association Study of Mammographic Density

Breast

Ronald A Depinho

Genetics and Biology of Pancreatic Ductal Adenocarcinoma

Pancreas

Pathology

Ulrike Peters

Detection of Colorectal Cancer Susceptibility Loci Using Genome-Wide Sequencing

Colorectum

Mathieu Lupien

Breast and Prostate Cancer Risk SNPs Regulate FoxA1 and Nuclear Receptor Activity

Prostate Breast