CRC Tier 1 - Determining why mutations of the metabolic enzyme isocitrate dehydrogenase cause leukemias and brain cancers

Robert J Wechsler-Reya

Cellular and Genetic Basis of Anaplastic Medulloblastoma

Brain, nervous system

Pediatric oncology or childhood cancer

Daniel Fowler

Combination Gene Therapy and Th1/Th2 Therapy

Leukaemia

Hematology and hematologic malignancies

Seth J Corey

Genetic Modifiers for Cancer Stem Cells in Secondary MDS/AML

Leukaemia

Pediatric oncology or childhood cancer Hematology and hematologic malignancies

Paul M Thompson

ENIGMA Center for Worldwide Medicine, Imaging & Genomics

Leukaemia

Katherine Warren

Preclinical Evaluation of Novel Therapeutics for CNS Tumor Therapy

Brain, nervous system

Aaron David Schimmer

Targeting the mitochondrial proteasome, ClpP, in AML

Leukaemia

Aaron David Schimmer

Targeting mitochondrial translation as a novel therapeutic strategy for AML

Leukaemia

James Kochenderfer

Autologous T cells Transduced with an Anti-CD19 Chimeric Antigen Receptor

Leukaemia

Hematology and hematologic malignancies

Xiaoyan Jiang

Molecular Targeting of Critical Domains of AHI-1 Oncoprotein in Chronic Myeloid Leukemia Stem Cells Resistant to Current Tyrosine Kinase Inhibitor Therapy

Leukaemia