Project leads
Collaborators

Pathology

Projects	People	Posts
779	1885	2

William W Bachovchin

Using FAP to Selectively Target Epithelial Cancers

Melanoma of skin Non-Melanoma skin cancer

F. Rob Jackson

TUSM/T-NEMC CENTER FOR NEUROSCIENCE RESEARCH

Brain, nervous system

Malavika Raman

The Role Of p97-Chaperone Complexes In Protein Quality Control

Melanoma of skin All cancers but non-melanoma skin cancer

Noorjahan Panjwani

The Role of Galectins in Corneal Hem- and Lymphangiogenesis

Melanoma of skin All cancers but non-melanoma skin cancer

Daniel Herrick

The regulation of p63 expression and activation to multipotency in HBCs of the ol

Melanoma of skin All cancers but non-melanoma skin cancer

Michael D Forgac

Structure, mechanism and regulation of the V-ATPases

All cancers but non-melanoma skin cancer

Kevin A Goncalves

Role of Angiogenin in Hematopoietic Stem Cell Quiescence and Self-renewal

Brent H. Cochran

RNAi screen of the glioblastoma stem cell kinome under hypoxia and normoxia

Brain, nervous system

Claire L Moore

Regulation of eukaryotic mRNA polyadenylation by sustained stress

All cancers but non-melanoma skin cancer

Brian S Schaffhausen

Products of the Transforming Genes of Polyomavirus

G. Gary Sahagian

PerkinElmer Spectrum CT Optical Imager

Melanoma of skin All cancers but non-melanoma skin cancer

Sergio Fantini

Near-infrared spectral imaging of the breast for cancer detection and monitoring

Dominique S Michaud

Microbiomes in Human Pancreatic Cancer

Charlotte Kuperwasser

Mechanisms of breast cancer associated with obesity

Mitch Mcvey

Mechanisms and consequences of inaccurate DNA double-strand break repair

Ana Soto

Mechanism of developmental toxicity of Bisphenol-A

Dominique S Michaud

Integrative Modeling of Gene Expression into GWAS of Glioma

Brain, nervous system

Kristina Cotter

Elucidating the Role of Plasma Membrane V-ATPases in Breast Cancer Metastasis

Laura Alice Stransky

Elucidating the mechanism of mTORC1 activation by amino acids

Karl Munger

Biological Activity of HPV E7 in Human Epithelial Cells

Charlotte Kuperwasser

Analysis of the cellular and molecular determinants of the human breast hierarchy

Jatin Roper

The role of Mtss1 in Hedgehog-mediated intestinal cancer stem cell function

Guo-Fu Hu

Mechanism of angiogenin-induced angiogenesis

All cancers but non-melanoma skin cancer

Andrew M Evens

MAP Kinase Signaling in Lymphoma: A Novel Therapeutic Paradigm

Non-Hodgkin lymphoma

Philip N. Tsichlis

Differential regulation of RNA processing by Akt isoforms

Trachea, bronchus and lung

Gregory F Oxenkrug

Depression, insulin resistance and xanthurenic acid in hepatitis C virus patients

Liver and intrahepatic bile ducts

Alain Charest

(PQB5)Molecular Wiring and Therapeutic Targeting of EGFR and PDGFR Signaling Network

All cancers but non-melanoma skin cancer

Jennifer A Lo

The roles of UV, neoantigens, and epitope spreading in vitiligo and melanoma

Melanoma of skin

George Sachs

The role of ArsS in gastric infection by Helicobacter pylori

Stomach Non-Hodgkin lymphoma

Joseph F Gera

Dysregulation of mTORC2 in gliomas

Brain, nervous system

Elliott D Kieff

Roles of Epstein-Barr virus nuclear antigens 2 and LP in B cell proliferation

Non-Hodgkin lymphoma Hodgkin lymphoma

David J. Kwiatkowski

Molecular Pathogenesis of the Hamartoma Syndromes

All cancers but non-melanoma skin cancer

Agnes B Kane

Training in Environmental Pathology

Melanoma of skin All cancers but non-melanoma skin cancer

Antonio Di Cristofano

Molecular analysis and therapeutic targeting of PI3K signaling in thyroid cancer

Theodore Brown

Impact of VEPH1 on cancer associated signaling pathways in the promotion of ovarian cancer

Madonna Peter

Discovery of novel methylation biomarkers in circulating DNA of metastatic castration resistant prostate cancer patients to improve treatment decisions

Benjamin Neel

Role of PTP1B in Her2+ breast cancer

Calum Macaulay

Real-Time In Vivo Oral Pathology for Clinical Decision Making

Lip, oral cavity

Calum Macaulay

Multi-Scale Tissue System's Biology approach to Identify Lethal Prostate Cancer

Wan Lam

An integrative approach to understand lung cancer development in smokers and non-smokers

Trachea, bronchus and lung

Robert Kridel

The pathogenic role of tumor-associated macrophages in Hodgkin lymphoma

Hodgkin lymphoma

David Huntsman

The Genetics of Hereditary Upper Gastrointestinal Cancers: Beyond CDH1 Germline Mutations

Stomach Pancreas Oesophagus Colorectum

Sohrab Shah

The clonal dynamics of ovarian cancers: phylogenetic models of chemosensitivity and resistance

Christian Steidl

Biology and clinical significance of the tumour microenvironment in lymphoid cancers

Non-Hodgkin lymphoma Hodgkin lymphoma

Andrew Weng

Adult vs. Fetal Programs in Leukemia Pathogenesis

Pathology Pediatric oncology or childhood cancer

Christine B. Ambrosone

Epidemiology of Breast Cancer Subtypes in African American Women: a Consortium

John J. Krolewski

An Androgen-Regulated Cytokine Network Controls Prostate Apoptosis.

Raghu Kalluri

Stromal Regulation of Bone Metastasis

Nicholas Navin

Single-Cell Sequencing of Breast Tumors to Investigate Genome Evolution

Suyun Huang

Signal Integration of Transcriptional Pathways in Gliomagenesis

Brain, nervous system

Andrew Andrew Futreal

Role of Tumor Stroma in Therapeutic Response and Resistance

Melanoma of skin

Jeffrey Nicholas Myers

Progression and Metastasis of Oral Tongue Cancer

Lip, oral cavity

Sue-Hwa Lin

Endothelial-to-osteoblast transition in prostate cancer bone metastasis

Keping Xie

Clinical Significance of Pancreatic Cancer Differentiation and Dedifferentiation

Shiaw-Yih Lin

Characterizing and Targeting CHD4 Deficiency in Endometrial Cancer

Ann M Killary

Biomarkers for the Early Detection of Pancreatic Cancer

Robert C Bast

ARHI (DIRAS3) in Autophagy and Dormancy of Ovarian Cancer

Sparreboom Alexander

Solute Carriers and Oxaliplatin Neurotoxicity

Douglas R Green

RIPK-dependent necrosis in development and cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Mary V. Relling

Center for Precision Medicine in Leukemia (CPML)

Heather S.L. Jim

Sickness Behaviors in Gynecologic Cancer Patients Treated with Chemotherapy

Alexander Robertson Allan Anderson

Predicting Prostate Cancer Aggressiveness

Robert J. Gillies

Imaging Habitats in Sarcoma

Robert J. Gillies

(PQC4) Habitats in Prostate Cancer

Charles L. Sawyers

Translational Research in Oncology Training Program

Melanoma of skin All cancers but non-melanoma skin cancer

Larry Norton

Program Project in Models of Breast Cancer

Amita Dave

Predictive MRI metrics for tumor aggressiveness in micropapillary thyroid cancer

Milind Rajadhyaksha

Peri-operative confocal imaging-guided laser ablation of basal cell carcinomas

Non-Melanoma skin cancer

James J-D Hsieh

Molecular Mechanisms of Impaired DAN Damage Response in Leukemia Pathogenesis

Malcolm C Pike

Hormonal effects on fallopian tube and ovary inclusion cysts, and ovarian cancer

Luc Gordon Trang Morris

Functionalizing recurrent FAT1 mutations and deletions in oral cancer

Lip, oral cavity

Ping Chi

Elucidating the roles of ETV1 in the pathogenesis of GIST

Christine Mayr

Dissecting the role of alternative 3UTRs in cancer with 3-seq

Melanoma of skin All cancers but non-melanoma skin cancer

Jacob Houghton

Developing an Anti-sialyl-Lewisa Diabody for ImmunoPET Imaging of Pancreas Cancer

David B. Solit

Defining the temporal sequence of PI3K pathway mutations in bladder cancer

Peter J Allen

Biomarker validation for intraductal papillary mucinous neoplasms of the pancreas

Efsevia Vakiani

Biological characterization of matched primary colorectal carcinomas & metastases

William Mallory Grady

Identify and validate novel epigenetic molecular markers for colorectal neoplasm

Christine A Iacobuzio-Donahue

(PQB6) Genetics of Subclonal Evolution in Pancreatic Cancer

Clinton Kylie Matson

Exploiting the Genomic Programs Underlying AR-Independent Prostate Cancer

Jerald Patrick Radich

The Genetics of Post-Transplant Relapse in Myeloid Malignancy

Christopher I Li

Discovery and verification of novel biomarkers of colorectal cancer recurrence

Thomas Spies

Stimulation of Tumorigenesis by NKG2D

Polly A. Newcomb

Serrated Colorectal Cancer: An Emerging Disease Subtype

Minna Roh

Cell Biological Mechanisms of Melanoma Cell Motility in vivo

Melanoma of skin

Julia E Maxson

Pathogenic Mechanisms of CSF3R Mutations in Leukemia

Christopher S Carlson

Monitoring disease progression in follicular lymphoma with next-gen sequencing

Non-Hodgkin lymphoma

Ulrike Peters

Molecular pathological epidemiology of colorectal cancer

Brian J Reid

Barretts Esophagus: Predictors of Progression

Janet L Stanford

Aggressive Prostate Cancer: Linking Epigenomics and Genetics for Prevention

William Mallory Grady

(PQC1) Accelerated biological aging and colon polyp to cancer progression

Levi A. Garraway

Systematic Genetic Characterization of African American Prostate Cancer

Kimmie Ng

Role of Vitamin D, Inflammation, and Energy Balance in Colorectal Cancer Survival

William C Hahn

Regulation and function of IKKe in breast cancer initiation and maintenance

Anthony G Letai

Investigation of therapeutic modulators of apoptotic priming in pancreatic cancer

Jens G Lohr

Determining the mutational landscape of circulating multiple myeloma cells

Multiple myeloma and immunoproliferative diseases

Matthew L Freedman

Defining the epigenetic landscape in human prostate cancer

Margaret A Shipp

Complementary Signaling Pathways In Hodgkin Lymphoma and Related Malignancies

Hodgkin lymphoma

Xiaofeng Steven Zheng

Role of Rab1 in Cell Growth and Cancer

Sharon R. Pine

Sox9 signaling in lung adenocarcinoma

Trachea, bronchus and lung

Estela Jacinto

Cotranslational Functions of MTOR

Melanoma of skin All cancers but non-melanoma skin cancer

Michael P Verzi

Transcriptional Mechanisms of Tumor Suppression

Michael L Gatza

A Pathway-based approach to investigate oncogenic mechanisms in ovarian cancer

Adana A.M. Llanos

Adipokines, adipokine receptors, and disparities in breast cancer clinicopathological features

Sanjiv S Gambhir

Optimization of an activatable photoacoustic agent to image thyroid cancer

Hanlee Ji

Oligonucleotide-Selective Sequencing for integrated and rapid cancer genome analy

Melanoma of skin All cancers but non-melanoma skin cancer

Jennifer Brady

Mechanisms governing tumor differentiation and metastasis

Trachea, bronchus and lung

Jonathan R Pollack

Mechanisms and targeting of SWI/SNF alterations in pancreatic cancer

Philip A Beachy

Epithelial/stromal signaling in bladder and prostate cell proliferation

Prostate Bladder

Rosalynd Denise Upton

Elucidating the Molecular Basis of Metastatic Prostate Cancer Cell Progression

Hamilton Courtney Hodges

Dynamic effects of cancer mutations on the mammalian SWI/SNF ATPase Brg

Melanoma of skin All cancers but non-melanoma skin cancer

Zijie Sun

A New Mechanism for Castration Resistant Prostate Cancer

Walter Gwang-Up Park

A Clinical Center to Study Immunological and Hormonal Biomarkers for the Diagnosis, Prediction and Treatment of Chronic Pancreatitis and its associated development to Diabetes and Pancreas Cancer

John B Sunwoo

(PQB2) Identification of Tumor-Derived Activators of Anti-Cancer Immune Responses

Melanoma of skin

Rulla M Tamimi

Mammographic density and texture features in relation to breast cancer risk

Vipul C Chitalia

Role of c-Cbl in Colon cancer

Eric Alan Moulton

Posterior cerebellar resection and pain processing in the pediatric brain

Brain, nervous system

Marsha A Moses

(PQA2): Escape from breast tumor dormancy: convergence of obesity and menopause

Andrew H Beck

Computational pathology to predict breast cancer risk in benign breast disease

Richard L Haspel

A National Curriculum in Cancer Genomics for Pathology Residents

Melanoma of skin All cancers but non-melanoma skin cancer

C Kent Osborne

Translational Research in Breast Cancer (SPORE)

Elizabeth Chiao

The Effectiveness of Screening HIV-Infected Women for Anal Cancer Precursors

Joanne S. Richards

Steroid Hormones Regulate Ovarian Cancer Progression and Metastasis

Benny Abraham Kaipparettu

Mitochondria-nuclear crosstalk in triple negative breast cancer racial disparity

Xiaosong Wang

Integrative Consig: NLK as Attractive Drug Target for Intractable Breast Cancer

David Alan Bader

Functional Investigation of the Mitochondrial Pyruvate Carrier in Prostate Cancer

Nya D Nelson

Elucidating the role of TIN2L at the telomere and in dyskeratosis congenita

Lip, oral cavity Leukaemia

William E Fisher

ALTERED MICROBIOME IN PANCREATITIS, DIABETES AND PANCREATIC CANCER

Qizhi C. Yao

A novel miR-198 replacement therapy for pancreatic cancer

Show more